New York State Police have issued a missing vulnerable adult alert for 78-year-old William Caloroso. He has Alzheimer's disease and may need some medical help.

He went missing Sunday night from River Road in the Town of Nichols, in Tioga County, and was last spotted in the Jamestown area, so Western New York keep your eye out.

Caloroso was driving a 2010 dark blue Chevy Impala with license plate number GDY-8262.

If you have any info, please call New York State police at (607) 561-7400.