Who will be Mario Williams first opponent when the Buffalo Bills open the 2012-13 season, and when will he play against his former team the Houston Texans. How about that Brady/Williams match-up? We'll find out tonight at 7pm when the NFL releases regular season schedules.

The Bills opponents have been determined for some time now, but when is still the looming question. Matchups against former Bill Marshawn Lynch and the Seattle Seahawks and a rare game against the San Francisco 49er's highlight the Bills NFC opponents while the team makes the short trip to Cleveland at some point. One thing is certain, the Bills can't afford a slow start nor can they afford the type of letdown they had last year. How the schedule lays out may go a long way to determining weather they will be in contention late in the season.

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